Author
Hidetoshi Kono
Recent research
- Biology
Impact of Intercalators on the Properties of DNA Analyzed by Molecular Dynamics Simulations
Abstract Intercalation of small molecules between DNA base pairs affects DNA conformation, disrupting essential cellular processes, including replication, transcription, and repair. We investigated conformational changes in 18-mer DNA upon intercalation of doxorubicin, SYBR Gold,...