Hideki Shigematsu

Cryo-EM structures of the SurA–BAM complex reveal conformational changes in outer membrane protein assembly

The outer membrane (OM) of Gram-negative bacteria acts as a permeability barrier against toxic compounds. Its integrity is maintained by various outer membrane proteins (OMPs), which are inserted into the OM by the β-barrel assembly machinery (BAM) complex. The periplasmic chaper...