Helmut Piazena

Engineering and characterization of a novel hydrogel-based cancer spheroid system to recapitulate clinical wIRA -hyperthermia treatments

Background Water-filtered infrared-A (wIRA) mild hyperthermia (mHT) combined with radiotherapy can effectively treat superficial tumors. While in vitro models are essential for mechanistic studies, existing approaches mostly rely on monolayer cultures and non-clinical heating. We...