Hefei Ren

Targeting the circ_0042819-PLA2G6 axis sensitizes multiple myeloma to proteasome inhibitors through ferroptosis induction

Multiple myeloma (MM) is a refractory plasma cell neoplasm characterized by frequent development of drug resistance, leading to poor clinical outcomes. Activation of ferroptosis, an iron-dependent form of cell death driven by lipid peroxidation, has emerged as a promising cancer...