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Stage-dependent activation of the circulating AIM2–caspase-1–GSDMD axis in silicosis: a cross-sectional study

Silicosis is a progressive occupational lung disease caused by long-term inhalation of crystalline silica, in which persistent inflammation contributes to lung injury and fibrotic remodeling. Experimental studies suggest that DNA-sensing pathways involving AIM2 may be engaged aft...