Harno Dwi Pranowo

Synthesis, Cytotoxicity Assay, and Network Pharmacology of 2-Acetylthiophene-based Chalcone Epoxide Derivatives as Anticancer Agents

A series of 2-acetylthiophene-based chalcone epoxides, their activity assays against cancer cells, and network pharmacology studies have been conducted. The synthesis of chalcone epoxides 3a-d afforded solid products in yields ranging from 56% to 91%. Biological screening reveale...