Author
Harald Schwalbe
Recent research
- Health & MedicineOpen access
Small Molecule Modulation of TERRA RNA Quadruplex Reprograms ALT‐Telomere Maintenance
ABSTRACT Telomeric repeat–containing RNA (TERRA) plays a central role in telomere maintenance in telomerase‐negative cancers that employ the alternative lengthening of telomeres (ALT) pathway; however, its RNA G‐quadruplex (rG4) structures remain underexplored as chemical targets...