Haotian Sun

Epitope and immunological basis for superior immunogenicity of henipavirus glycoprotein HeV.G over NiV.G in mRNA vaccines

Nipah (NiV) and Hendra (HeV) viruses are highly lethal zoonotic Henipaviruses with pandemic potential, for which no licensed vaccines exist. The surface glycoprotein (G) is the primary target of neutralizing antibodies, yet a systematic comparison of the immunogenicity of NiV.G a...