Haodong Yuan

Cellular crosstalk of fibroblast–myofibroblast transition in intestinal homeostasis and disease

Fibroblasts are central components of the intestinal microenvironment and can acquire a myofibroblast phenotype through fibroblast-to-myofibroblast transition (FMT), a process linked to increased tissue mechanosensitivity and active extracellular matrix (ECM) remodeling. In this...