Hans-Christian Reinecker

Adherent-invasive Escherichia coli pduB drives vitamin B 12 -dependent colitis in mice

ABSTRACT Adherent-invasive Escherichia coli (AIEC) are strongly implicated in the pathogenesis of Crohn’s disease, but the virulence factors driving their invasive and pro-inflammatory behavior remain incompletely defined. Here, we demonstrate that vitamin B 12 availability modul...