Hanne Gredal

ABCB1 Frameshift Deletion in Skye Terriers With Potential Pharmacogenetic Relevance

Ivermectin-associated neurotoxicity is a potentially life-threatening condition caused by disruption of the ABCB1 encoded P-glycoprotein drug transporter in certain dog breeds. Skye terriers are considered at increased risk of ivermectin toxicity despite the absence of an identif...