Hannah Carlisle

Rational Design of a Synthetic Galliphore for the Diagnostic Nuclear Imaging and Treatment of Bacterial Infections

ABSTRACT We introduce a solid‐phase synthesis platform for the rapid, modular, and scalable synthesis of the synthetic metallophore KO‐NH 2 , which is readily recognized by bacterial siderophore transporters, but has optimized affinity for Ga 3+ over Fe 3+ . Four synthetic protoc...