Han Zhang

Inflammatory Endothelium‐Targeted Carbon Dot Nanozymes for Exogenous Enzyme Supplementation and Synergistic Regulation in Acute Lung Injury

ABSTRACT Acute lung injury (ALI) features vascular endothelial damage, impaired barrier function, and excessive ROS accumulation, which depletes endogenous peroxidases and disrupts redox homeostasis. Transcriptomic comparison between control and ALI model groups verified marked d...

Lactylation-related immune-metabolic dysregulation defines prognostic and therapeutic stratification in lung adenocarcinoma

Background Lactylation links lactate metabolism with inflammatory signaling and immune regulation in tumors. However, its cellular distribution and translational value in lung adenocarcinoma (LUAD) remain unclear. Methods Single-cell RNA-sequencing datasets GSE189357 and GSE17114...