Hamid Bellout

A Generalization of the Ternary Binding Model to Membrane‐Confined Systems With Finite Copy Number

ABSTRACT The standard Douglass ternary binding model (TBM) for three‐body equilibria assumes a well‐mixed, three‐dimensional solution. When applied to bispecific T‐cell engagers (BiTEs), however, the productive trimeric complex forms not in bulk solution but within a nanoscale me...