Hajime Matsushima

Protocol for a phase I/II, open-label, single-arm trial of autologous chemically induced liver progenitor (CLiP) cell transplantation in patients with decompensated cirrhosis

Introduction Decompensated cirrhosis is associated with a poor prognosis and limited therapeutic options for patients who are not candidates for liver transplantation. Although various cell-based regenerative therapies have been investigated, their clinical benefits are limited....