Haifa Alharbi

Molecular modelling, cytotoxic activity, and carbonic anhydrase inhibition of new pyridazine-thiazole hybrid compounds

A series of novel pyridazine-thiazole compounds 6 , 7 , 9 , and 10 were synthesized by introducing various thiazole ring systems into the precursor 4-(pyridazin-3-yl)amino)benzohydrazide compound 4 . The DFT/B3LYP optimized structures of the synthesized hybrids exhibited a non-pl...