Guoxu Ling

Activation of PPARγ attenuates neuropathic pain by modulating spinal cuproptosis-associated mitochondrial dysfunction and neuroinflammation

Abstract Cuproptosis is a recently identified form of programmed cell death driven by copper accumulation. Increasing evidence suggests that copper dyshomeostasis contributes to neuroinflammatory processes. Peroxisome proliferator-activated receptor gamma (PPARγ) activation has b...