Guoping Zhao

Biliary microbiota associated with early postoperative stone reappearance under T-Tube surveillance: an exploratory 16 S rRNA sequencing study

Early postoperative stone reappearance after biliary surgery may reflect residual stones, early re-formation, or bile duct recolonization within an altered biliary environment. Although mechanical and anatomical factors are traditionally implicated in recurrent common bile duct s...

CIP2A–TOPBP1 complex and PP2A dynamically regulate Polθ recruitment and phosphorylation at mitotic DNA double-strand breaks

DNA double-strand breaks (DSBs) that occur during mitosis are primarily repaired by Polθ-mediated microhomology-mediated end joining (MMEJ). The CIP2A–TOPBP1 complex has been shown to tether broken chromatin at mitotic DSBs, but whether it coordinates with or functions independen...