Guohua Zhu

Early SOX9 Activation Primes Hippo– YAP / TAZ Rewiring During Glioblastoma Stemness Acquisition

Glioblastoma progression is driven by stemness acquisition and cellular plasticity, yet the temporal and spatial organization of these processes remains incompletely defined. In this study, single-cell RNA sequencing, pseudotime reconstruction, spatial transcriptomics, and in vit...