guohu zhang

A Bridge From the Gut: Azithromycin Links to AMPK/SIRT1 Activation, Rectifies Th17/Treg Balance and Alleviates COPD Associated With Gut Microbiota-TMAO Modulation

Background: The intestinal microbial ecosystem has emerged as an important contributor to chronic obstructive pulmonary disease (COPD) pathogenesis. Azithromycin (AZI), a commonly used therapeutic agent for COPD, has antibacterial and anti-inflammatory effects. This study aims to...