Guo Zhuling

Artificial Intelligence in Dentistry: Integrated Applications and Specialty-Specific Advances

Artificial intelligence (AI) is transitioning from a supportive tool to a core component of clinical decision-making in dentistry. This review synthesizes advances in deep learning and machine learning for oral disease diagnosis, orthodontic treatment prediction, pediatric oral h...

Tactical Paralysis: The Interplay Between Chikungunya Virus and Host Mitochondrial Dynamics in Immune Evasion and Metabolic Remodeling

Chikungunya virus (CHIKV) is an expanding alphavirus causing acute febrile illness, yet its most debilitating signature remains the refractory chronic arthralgia persisting for months or years. While traditional paradigms focused on viral-mediated host shutoff, emerging evidence...

Deciphering the AGEs-RAGE Signaling Network in Diabetes-Associated Periodontitis: Pathogenic Mechanisms and Emerging Targeted Therapies

Objectives: To summarize the role of the AGEs-RAGE axis in diabetes-associated periodontitis and evaluate potential targeted therapies. Materials and Methods: Recent literature on molecular mechanisms and therapeutic strategies involving the AGEs-RAGE pathway in diabetic periodon...