Gültekin Tamgüney

Fecal Aβ and tau aggregates are elevated in cognitive impairment and reveal peripheral proteopathic alterations

Abstract Background Aggregation of amyloid-β (Aβ) and tau is central to Alzheimer’s disease (AD) pathogenesis and forms the basis of established cerebrospinal fluid (CSF) and imaging biomarkers. However, increasing evidence suggests that AD involves systemic processes beyond the...