Guilian Yang

TGF-β3 derived from CD8+ T cells plays an important role in the lungs of piglets infected with SIV

The swine is considered an important host for the production of pandemic influenza viruses, and studying the immune characteristics of swine influenza virus (SIV) infection in piglets is crucial for pandemic prevention. Here, we used single-cell sequencing (scRNA-seq) to demonstr...

Synthetic microbial communities: emerging live biotherapeutics for targeted gut microbiome modulation

Gut microbiome dysbiosis causes various intestinal diseases. However, an undefined composition and potential biosafety risks limit the applicability of traditional fecal microbiota transplantation (FMT). Synthetic microbial communities (SynComs), which are compositionally defined...