Guangyu An

Deep Cavitand Mediated Selective Aerobic Oxidative Cyclization of Thiols to Cyclic Disulfides

Abstract A mild supramolecular template strategy is reported for the selective synthesis of medium- to macrocyclic disulfides via aerobic oxidative cyclization of α,ω-dithiols in aqueous media. The water-soluble deep cavitand CV-1 serves as a multifunctional platform that synergi...