Guangxi Zhou

KARAP Deficiency Alleviates Intestinal Mucosal Barrier Dysfunction by Regulating Mitochondrial Homeostasis in Macrophages

Abstract Background Killer cell activating receptor-associated protein (KARAP) has been implicated in the progression of various inflammatory and immune-mediated diseases, including ulcerative colitis (UC). Although macrophages play a pivotal role in UC pathogenesis, how KARAP re...