Guangtong She

Integrative genomic and functional analysis identifies BCL10 as a novel driver of trophoblast senescence in preeclampsia

OBJECTIVE: To identify senescence-driving genes causally linked to preeclampsia (PE) and to elucidate impact on placental dysfunction. METHODS: Placental RNA-seq data set GSE234729 was analyzed for differentially expressed genes. Weighted gene co-expression network analysis was u...