Guangjun Jiao

NIR‐Responsive CaMoO 4 /Mo 3 N 2 Heterojunction Modified Biomimetic Periosteum: Synergistic Anti‐Infection and Promotion of Bone Defect Repair

ABSTRACT Treating infected bone defects remains a formidable clinical challenge due to robust bacterial antioxidant resistance and severe microenvironmental deterioration. Herein, an antibacterial biomimetic periosteum (ABP) is rationally engineered by in situ anchoring ultrasmal...

Dual-targeted bioengineered bacterial extracellular vesicles ameliorate senile osteoporosis via SAE1-mediated NAT10 SUMOylation and ac4C-dependent glycolysis

Senile osteoporosis (SOP) is an age-related skeletal disease characterized by progressive bone loss and the deterioration of bone microarchitecture. Promoting the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is a potential strategy for SOP intervention...