Guang Xiong

Joint associations of comorbidity burden and polypharmacy with depressive symptoms, and joint effects of comorbidity burden, polypharmacy, and depressive symptoms on all-cause mortality among US adults aged 45 years and older: a dual cross-sectional and cohort study

Although comorbidity burden and polypharmacy are increasingly prevalent among middle-aged and older adults and may contribute to depressive symptoms, evidence on their joint associations remains scarce. Furthermore, the combined impact of comorbidity burden, polypharmacy, and dep...