Guang Li

Platelet miRNAs for early diagnosis of Kawasaki disease: development and internal validation of a clinical model

Early diagnosis of Kawasaki disease (KD) remains challenging, particularly in incomplete or early-stage cases, increasing the risk of coronary artery complications. Platelet-derived microRNAs (miRNAs) are implicated in KD pathogenesis, but standardized normalization and validated...

Multi-algorithm consensus clustering identifies four subphenotypes in sepsis-associated acute kidney injury

Sepsis-associated acute kidney injury (SA-AKI) is a highly heterogeneous syndrome with variable clinical trajectories and outcomes. Conventional staging systems, such as KDIGO, fail to capture this heterogeneity, limiting risk stratification and personalized management. We aimed...