Gregory R. Madden

Propensity-matched case control study of anti-interleukin-23 therapies in Clostridioides difficile Infection

Abstract Background Clostridioides difficile infection remains a major cause of infectious morbidity and mortality, largely driven by a dysregulated, toxin-mediated host immune response that current pathogen-targeted therapies fail to address. Interleukin-23-driven Th17 responses...