Grégoire Manaud

Wild-type and mutated ß-catenin differently repress RND3/RHOE expression in hepatocellular carcinoma

Tumor development and progression are mainly driven by oncogenic mutations but are also regulated by physical factors. Through its structural and transcriptional functions, ß-catenin is a key factor that acts on both aspects to promote liver tumorigenesis, leading to hepatocellul...