Grégoire D’Andréa

Comprehensive proteomic and structural mapping of post-translational modifications of human thyroglobulin

Human thyroglobulin (hTg) is the precursor of thyroid hormones (TH) and a major iodine reservoir in the thyroid gland. Its maturation and function critically depend on multiple post-translational modifications (PTMs). To date, their global distribution, structural organization an...