Graham M. Donovan

Self-organized ventilation defects in asthma: insights and open-source implementation of the Venegas–Winkler model

Abstract The Venegas–Winkler model is a seminal model in asthma pathophysiology, providing both a conceptual and quantitative framework for extending a posited bistability between open and closed states at the level of the individual, terminal airway to the lung as a whole. In do...