Grace Victoria Poo

Quinoline-Based Amide Foldamers with One-Handed Chirality Induced by an Asymmetric Plane

Abstract A quinoline-containing cyclophane derivative with planar chirality was rationally designed and synthesized based on [2.2]paracyclophane (PCP) and used as a structural unit to induce the absolute one-handed helical conformation of quinoline foldamers. 1H NMR, X-ray crysta...