Gong Cheng

Multivalent antiviral conjugates enhance activity against Influenza via cross-linking viruses

Abstract Long-acting drug–Fc conjugate (CD388) has emerged as a new class of antivirals against influenza A and B, yet the mechanisms governing how Fc conjugation reshapes small-molecule function remain undefined. Here we establish a programmable multivalent antiviral conjugates...

Undernutrition enhances host attractiveness to mosquitoes and transmission of mosquito-borne diseases

Undernutrition is prevalent in regions affected by mosquito-borne diseases. Understanding how insufficient nutrition affects the transmission of mosquito-borne pathogens is critical for combating these diseases. In this study, we found that undernourished mice were more attractiv...