Gökhan Özokan

Sequence-Controlled Synthesis of Heteroaryl-Substituted Decahydroacridine-1,8-diones: Comparative Evaluation of Preformed Enaminone and Multicomponent Routes

Six 9-thienyl-10-aryl-substituted 3,3,6,6-tetramethyl-decahydroacridine-1,8-diones (5a–f) were prepared by two acid-mediated routes that used the same solvent, temperature, and reaction time. In the sequential route, preformed 5,5-dimethyl-3-(arylamino)cyclohex-2-enones were reac...