Giuseppe Palmieri

Impact of methylation and mutation modifications on melanoma progression through evaluation of paired primary and secondary lesions from same patients

Cutaneous melanoma is a complex disease whose progression is driven by alterations in both gene pathways and epigenetic mechanisms that may continue to evolve through the disease course. Among epigenetic alterations, gene methylation has been reported to play an important role in...

Discrepancies in the Molecular Epidemiology of Druggable Genetic Alterations in Non-Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) represents most lung cancer diagnoses worldwide and remains a leading cause of cancer-related mortality. The advent of precision oncology has transformed the therapeutic landscape of NSCLC through the identification of druggable genetic alterati...