Giulio Bertuzzi

Polar and e-Radical Strain-Release Strategies for Accessing Functionalized 2-Oxabicyclo[2.1.1]hexan-3-ones from Bicyclo[1.1.0]butanes

Abstract 2-Oxabicyclo[2.1.1]hexanes (OBHs) have emerged as valuable saturated aromatic replacements, whereas their lactone analogues, 2-oxabicyclo[2.1.1]hexan-3-ones (OBHOs) remain underexplored, because of limited synthetic access. Herein, we report complementary polar and elect...