Giulia Marsico

Efficient Synthesis of the Fungal Phytotoxin (±)-3-Deoxyradicinin

An efficient synthesis of phytotoxin (±)-3-deoxyradicinin was developed from commercially available 4-hydroxy-6-methyl-2H-pyran-2-one. The propenyl side chain was introduced through regioselective bromination followed by Horner–Wadsworth–Emmons olefination, while the second pyran...