Gisele Macêdo Rodrigues da Cunha

Immunization withthe Tc85-Derived Peptide Displayedon Virus-like Particles Confers Protection against Trypanosoma cruzi Infection

Abstract Chagas disease, caused by the Trypanosoma cruzi, remains a major global health burden with limited prophylactic options. We describe a vaccine platform that leverages a peptide epitope derived from the T. cruzi trans-sialidase group II (Tc85pep), displayed on the virus-l...