Giampiero Leanza

Addressing the Limits of Emx2 Therapy of Glioblastoma Multiforme by Transgene Insulation and Epigenetic Pharmacological Intervention

Introduction/Objectives: Implicated in the regionalization of the anterior central nervous system (CNS) and the progression of pallial astrogliogenesis, the transcription factor gene EMX2 has been reported to be specifically silenced in several tumors, both non-neural and neural....