Gerardo Aguirre-Hernández

Design, synthesis, drug-likeness, and molecular dynamics evaluations of monobrominated amathamide G analogs as potential ligands for D2-like dopamine receptors

Abstract Dopamine receptors (DRs) are key modulators of physiological and behavioral responses in the central nervous system (CNS), playing a major role in psychotic disorders. Among these, the D2-like members D2R, D3R and D4R are particularly attractive therapeutic targets for t...