Geovanni Dantas Cassali

Mammary secretory carcinoma in a female domestic rabbit (Oryctolagus cuniculus): histopathological and immunohistochemical features

Abstract Secretory carcinoma of the breast is a rare histological subtype in women and is uncommon in female dogs and cats, with only two cases described in female dogs and one case described in a cat. This report describes the histopathological and immunohistochemical features o...

Noninvasive malignant mammary adenomyoepithelioma in a male cat

Abstract This report describes the histopathological and immunohistochemical findings of a noninvasive malignant mammary adenomyoepithelioma in a seven-year-old neutered male mixed-breed cat. The animal was euthanized due to an extensive mandibular fracture caused by squamous cel...

Preclinical Evaluation of Combined Polo-like Kinase 1 Inhibition and Navitoclax in Experimental Models of Lung Cancer

Targeted therapies have substantially advanced cancer treatment; however, therapeutic resistance remains a major challenge, particularly in lung cancer. Polo-like kinase 1 (PLK-1), a key regulator of mitosis, is frequently overexpressed in lung tumors and has emerged as an attrac...