Georg Gasteiger

STAT3 operates as an inflammation-dependent transcriptional switch in antiviral NK cells

The immune system integrates signals to regulate immune responses, forming complex context-dependent networks where identical cues produce distinct outcomes. Signal transducer and activator of transcription (STAT) transcription factors convert cytokine receptor engagement into tr...

Cytomegalovirus Latency Fuels Inflammation Following Myocardial Infarction

BACKGROUND: Epidemiological studies have consistently associated cytomegalovirus (CMV) seropositivity with adverse cardiovascular outcomes. However, the mechanisms by which cytomegalovirus infection impacts pathophysiology in the heart remain poorly understood. In this study, we...