Gareth J. McKay

Transcriptomic insights into diabetic kidney disease: a systematic review of RNA sequencing studies

Abstract Background Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease and end-stage kidney disease worldwide. Despite shared clinical risk factors, substantial inter-individual variability exists in DKD susceptibility and progression, suggesting an import...

Fermented dairy intake and markers of musculoskeletal ageing on the island of Ireland: insights from the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) and The Irish Longitudinal Study on Ageing (TILDA)

Abstract Purpose Fermented dairy foods may support healthy musculoskeletal ageing via high-quality protein and gut-muscle axis modulation. Epidemiological evidence linking fermented dairy foods with physical function in older adults is limited. We examined associations between fe...

Accelerated Epigenetic Ageing in Diabetic Kidney Disease: A Comparison of 10 Epigenetic Clock Measures in Individuals With Type 1 Diabetes

To characterize accelerated epigenetic ageing in individuals with diabetic kidney disease (DKD) and type 1 diabetes, 10 epigenetic clocks were generated for those with type 1 diabetes, with (case patients) or without (control participants) DKD, within the All Ireland–Warren 3–Gen...