Gamze Gürsoy

Privacy-preserving pangenome graphs

Abstract The human pangenome reference, often represented as a graph, promises to capture genetic diversity across populations, but open release of individual haplotypes raises significant privacy concerns, including risks of re-identification and inference of sensitive traits. T...

Private information leakage from polygenic risk scores

Abstract Polygenic Risk Scores (PRSs) estimate the likelihood of individuals to develop complex diseases based on their genetic variations. While their use in clinical practice and direct-to-consumer genetic testing is growing, the privacy implications of publicly sharing PRS val...