Gabriele Multhoff

Association of Preoperative Circulating Hsp70 Levels with Event-Free Survival in Thoracic Oncology

Objectives/Background: Heat shock protein 70 (Hsp70) is frequently overexpressed and released from malignant tumors and is associated with tumor aggressiveness and resistance to treatment. While elevated levels of extracellular Hsp70 (eHsp70) in the blood have been associated wit...

Patient-derived 3D organotypic co-cultures as a long-term ex vivo model for pleomorphic adenoma of the parotid gland

Abstract Pleomorphic adenoma is the most common benign salivary gland tumor and most frequently arises in the parotid gland. Although benign, it can recur and may undergo malignant transformation, underscoring the need for experimental models that preserve native tissue features...