G. S. M. Kiruba

Gas Phase Studies of Purine Base Analogs: Intrinsic Properties and Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase (HG(X)PRT)

Abstract The gas-phase acidity and proton affinity of purine nucleobases that are found to be inactive for the enzyme Plasmodium falciparum hypoxanthine-guanine-(xanthine) phosphoribosyltransferase (Pf HG(X)PRT) have been examined using both computational and experimental methods...