Fuyuan Zheng

Low Dasatinib Penetration of the Blood–Brain Barrier in Children With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: Evidence From LC‐MS/MS Analysis

ABSTRACT We measured dasatinib concentrations in paired plasma and cerebrospinal fluid (CSF) samples from children with Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL). Blood samples were collected from children at 0 h (pre‐dasatinib) and 2 h post‐dasatini...