Fumi Nagatsugi

Photocatalytic proximity labeling for the identification of G-quadruplex DNA-interacting proteins

Abstract DNA–protein interactions play an essential role in fundamental cellular biological processes. Herein, we report a photocatalytic proximity labeling approach for the broad screening of G-quadruplex (G4)-interacting proteins (G4IPs) using human telomere G4 DNA modified wit...

Photo-triggered construction of nitrogen-containing aromatic heterocycles under physiological conditions

Abstract Precise spatiotemporal control of molecular function is essential for probing biological systems and developing safer therapeutics. Herein, we review photoinducible intramolecular cyclization reactions developed in-house for generating nitrogen-containing aromatic hetero...